Dr Chan Hwei Wuen is a Senior Consultant and Ophthalmic Surgeon at the Department of Ophthalmology, National University Hospital (NUH) and Alexandra Hospital. Dr Chan serves as Program Director of the Ophthalmology Residency Program, National University Health Systems. She holds a joint appointment on the National University of Singapore (NUS) Clinical Faculty Scheme as an Assistant Professor in Ophthalmology, Yong Loo Lin School of Medicine, NUS.
Dr Chan received formal medical training at the University College London (UCL) and her first exposure to Ophthalmology was during her time at Moorfields Eye Hospital as an undergraduate, which fuelled her interest to pursue a career in this specialty. She completed residency training in Ophthalmology at the NUH and served as the Chief Resident. She was and remains actively involved in undergraduate and postgraduate teaching and was awarded the NUS MedSoc Outstanding Tutor Award and NUS Special Recognition Award for undergraduate medical teaching.
Upon completion of local fellowship training in Medical Retina and Vitreoretinal Surgery, as well as Visual Electrophysiology with Prof Graham Holder, Dr Chan pursued advanced subspecialty training in the UK and Belgium as a recipient of the MOH Health Manpower Development Plan (HMDP) fellowship award. During her time at Moorfields Eye Hospital, she was trained in paediatric and adult Ophthalmic Genetics under Prof Andrew Webster, Prof Michel Michaelides, Prof Mariya Moosajee and Prof Omar Mahroo. Her time at the Ghent University Hospital, Belgium was spent under the tutelage of Prof Bart Leroy in Ophthalmic Genetics where she was involved in several gene therapy clinical trials including Luxturna for the treatment of biallelic mutation in RPE65 mutation-related inherited retinal dystrophy and Sepofarsen for CEP290-associated Leber Congenital Amaurosis.
Dr Chan is a specialist in both medical and surgical retina with a special interest in Inherited Retinal Diseases (IRD) and Ophthalmic Genetics. She currently leads a dedicated IRD service at NUH for local and international patients. Her main research areas include phenotype-genotype correlation studies in IRD with a special interest in ABCA4-related retinopathy for which she was awarded the NMRC Clinician Scientist Individual Research Grant New Investigator Grant (CS-IRG-NIG) and RNA-based therapeutics. Dr Chan is a founding member of the EURETINA IRD & Paediatric Retina Subspecialty Group and the Royal College of Ophthalmologists (UK). Aside from her sub-specialty interests, Dr Chan also has a keen interest in complex cataract surgery.
