Dr Yuen, an ASEAN Scholar and graduate of the National University of Singapore (NUS), is an Assistant Professor in the Department of Ophthalmology at NUS and a Senior Consultant, Ophthalmologist with the Department of Ophthalmology at National University Hospital (NUH). He also serves as the Director of Undergraduate Education for the NUS Department of Ophthalmology.
A femtosecond laser-accredited cataract surgeon, Dr. Yuen has sub-specialty expertise in vitreoretinal surgery, uveitis (ocular Inflammation) and complex cataract surgery. He was conferred the Ministry of Health’s Health Manpower Development Plan (HMDP) award and has been an invited speaker at both local and international conferences, including Euretina and the International Ocular Inflammation Society Congress.
Dr Yuen’s practice focuses on managing complex cataracts, particularly in uveitis patients, as well as the medical and surgical treatment of diabetic eye disease, age-related macular degeneration and retinal detachment. His expertise includes handling challenging cataract cases such as:
• Small pupils
• Posterior polar cataracts
• Subluxed/dislocated lenses
• Scleral-fixated lenses
• Implantation of premium intraocular lenses
In retinal surgery, he is proficient in the latest techniques, including 27G small-gauge vitrectomy and scleral buckling, skills he honed during his overseas fellowship with A/Prof Jagjit S Gilhotra, one of the largest users of 27G vitrectomies in Australia. Dr Yuen is also actively involved in advancing medical and surgical retina treatments, ensuring that NUH remains at the forefront of innovation.
In 2025, Dr Yuen became the first surgeon in Singapore and Southeast Asia to perform the first five port delivery platform implant surgeries for age-related macular degeneration. These procedures were conducted at the NUH Department of Ophthalmology, introducing an innovative, long-term, refillable drug delivery system to reduce the burden of frequent anti-VEGF injections.
Additionally, Dr. Yuen was the first in Singapore to gain hands-on experience with intravitreal Vamikibart for uveitic macular edema as part of the SANDCAT trial, contributing to early clinical insights into this emerging treatment.
Passionate about medical education, Dr. Yuen has received the Junior Doctor Teaching Award, Young Teacher Award and the NUHS Teaching Excellence Award for his contributions to training future ophthalmologists. He has also served as an examiner and admissions interviewer for the NUS School of Medicine.
As part of the Core Faculty for the NUHS Ophthalmology Residency Programme, he plays a key role in training the next generation of ophthalmologists. Additionally, he is the designated specialist advisor for the National University Polyclinics (NUPs), where he conducts primary eye care courses for Internal Medicine and Family Medicine physicians.
Dr. Yuen is fluent in English, Mandarin and Malay.
1: Yuen YS, Holder GE, Lingam G, Shen TYT. Diffuse retinal dysfunction following immune reconstitution uveitis in patients with prior cytomegalovirus retinitis:a novel observation. Doc Ophthalmol. 2023 Oct;147(2):139-145. doi:10.1007/s10633-023-09947-6. Epub 2023 Aug 28. PMID: 37639171.
2: Seah I, Zhao X, Lin Q, Liu Z, Su SZZ, Yuen YS, Hunziker W, Lingam G, Loh XJ, Su X. Use of biomaterials for sustained delivery of anti-VEGF to treat retinal diseases. Eye (Lond). 2020 Aug;34(8):1341-1356. doi: 10.1038/s41433-020-0770-y. Epub 2020 Jan 30. Erratum in: Eye (Lond). 2020 Aug;34(8):1486. doi: 10.1038/s41433-020-0980-3. PMID: 32001821; PMCID: PMC7376230.
3: Lim SY, Wong WM, Seah I, Chan HW, Su X, Lingam G, Yuen YS. Treat and extend regimen for diabetic macular oedema-a systematic review and meta-analysis. Graefes Arch Clin Exp Ophthalmol. 2023 Feb;261(2):303-315. doi:10.1007/s00417-022-05770-y. Epub 2022 Jul 30. PMID: 35906415.
4: Thng ZX, Putera I, Testi I, Chan K, Westcott M, Chee SP, Dick AD, Kempen JH,Bodaghi B, Thorne JE, Barisani-Asenbauer T, de Smet MD, Smith JR, McCluskey P, La Distia Nora R, Jabs DA, de Boer JH, Sen HN, Goldstein DA, Khairallah M, Davis JL, Rosenbaum JT, Jones NP, Nguyen QD, Pavesio C, Agrawal R, Gupta V; TITAN consensus guidelines group. The Infectious Uveitis Treatment Algorithm Network (TITAN) Report 2-global current practice patterns for the management of Cytomegalovirus anterior uveitis. Eye (Lond). 2024 Jan;38(1):68-75. doi:10.1038/s41433-023-02631-8. Epub 2023 Jul 7. PMID: 37419958; PMCID: PMC10764804.
5: Agrawal R, Testi I, Bodaghi B, Barisani-Asenbauer T, McCluskey P, Agarwal A, Kempen JH, Gupta A, Smith JR, de Smet MD, Yuen YS, Mahajan S, Kon OM, Nguyen QD, Pavesio C, Gupta V; Collaborative Ocular Tuberculosis Study Consensus Group. Collaborative Ocular Tuberculosis Study Consensus Guidelines on the Management of Tubercular Uveitis-Report 2: Guidelines for Initiating Antitubercular Therapy in Anterior Uveitis, Intermediate Uveitis, Panuveitis, and Retinal Vasculitis. Ophthalmology. 2021 Feb;128(2):277-287. doi: 10.1016/j.ophtha.2020.06.052. Epub 2020 Jun 27. PMID: 32603726.
6: Lee PY, Oen KQX, Lim GRS, Hartono JL, Muthiah M, Huang DQ, Teo FSW, Li AY, Mak A, Chandran NS, Tan CL, Yang P, Tai ES, Ng KWP, Vijayan J, Chan YC, Tan LL, Lee MB, Chua HR, Hong WZ, Yap ES, Lim DK, Yuen YS, Chan YH, Aminkeng F, Wong ASC, Huang Y, Tay SH. Neutrophil-to-Lymphocyte Ratio Predicts Development of Immune-Related Adverse Events and Outcomes from Immune Checkpoint Blockade: A Case-Control Study. Cancers (Basel). 2021 Mar 15;13(6):1308. doi: 10.3390/cancers13061308. PMID: 33804050; PMCID: PMC8001500.
7: Yuen YS, Gilhotra JS, Dalton M, Aujla JS, Mehta H, Wickremasinghe S, Uppal G, Arnold J, Chen F, Chang A, Fraser-Bell S, Lim L, Shah J, Bowditch E, Broadhead GK. Diabetic Macular Oedema Guidelines: An Australian Perspective. J Ophthalmol. 2023 Feb 14;2023:6329819. doi:10.1155/2023/6329819. PMID: 36824442; PMCID:PMC9943607.
8: Agrawal R, Testi I, Mahajan S, Yuen YS, Agarwal A, Kon OM, Barisani-Asenbauer T, Kempen JH, Gupta A, Jabs DA, Smith JR, Nguyen QD, Pavesio C, Gupta V; Collaborative Ocular Tuberculosis Study Consensus Group. Collaborative Ocular Tuberculosis Study Consensus Guidelines on the Management of Tubercular Uveitis-Report 1: Guidelines for Initiating Antitubercular Therapy in Tubercular Choroiditis. Ophthalmology. 2021 Feb;128(2):266-276. doi:10.1016/j.ophtha.2020.01.008. Epub 2020 Jan 11. PMID: 32115264.
9: Yuen YS, Tan GSW, Gan NY, Too IHK, Mothe RK, Basa P, Shaikh J. Real-World Evidence in the Management of Diabetic Macular Edema with Intravitreal Anti-VEGFs in Asia: A Systematic Literature Review. Clin Ophthalmol. 2022 Oct 19;16:3503-3526. doi: 10.2147/OPTH.S378392. PMID: 36274678; PMCID: PMC9579008.
10: Agrawal R, Testi I, Mahajan S, Yuen YS, Agarwal A, Rousselot A, Raje D, Gunasekeran DV, Kon OM, Barisani-Asenbauer T, Kempen JH, Gupta A, Jabs DA, Smith JR, Bodaghi B, Zierhut M, DeSmet M, Cluskey PM, Agarwal M, Agarwal M, Aggarwal K, Agrawal M, Al-Dhibi H, Androudi S, Asyari F, Balasundaram MB, Murthy KB, Baglivo E, Banker A, Bansal R, Basu S, Behera D, Biswas J, Carreño E, Caspers L, Chee SP, Chhabra R, Cimino L, Del Rio LEC, Cunningham ET, Curi ALL, Das D, Denisova E, Denniston AK, Errera MH, Fonollosa A, George A, Goldstein DA, Crosier YG, Gurbaxani A, Invernizzi A, Isa HM, Md Islam S, Jones N, Katoch D, Khairallah M, Khosla A, Kramer M, Kumar A, Kumar A, Nora RD, Lee R, Lowder C,Luthra S, Mahendradas P, Makhoul D, Mazumdar S, Mehta S, Miserocchi E, Mochizuki M, Mohamed OS, Muccioli C, Munk MR, Murthy S, Narain S, Nascimento H, Neri P, Nguyen M, Okada AA, Ozdal P, Palestine A, Pichi F, Rathinam SR, Schlaen A, Sehgal S, Sen HN, Sharma A, Sharma K, Shoughy SS, Singh N, Singh R, Soheilian M, Sridharan S, Thorne JE, Tappeiner C, Teoh S, Tognon MS, Tugal-Tutkun I, Tyagi M, Uy H, Santos DVV, Valentincic NV, Westcott M, Yanai R, Alvarez BY, Zahedur R, Nguyen QD, Pavesio C, Gupta V. The Collaborative Ocular Tuberculosis Study (COTS) Consensus (CON) Group Meeting Proceedings. Ocul Immunol Inflamm. 2020 Sep 30;28(sup1):85-95. doi: 10.1080/09273948.2020.1716025. Epub 2020 Apr 6. PMID: 32250731.
