Care at NUH

Reproductive Endocrinology and Infertility

2025/02/14
The Division of Reproductive Endocrinology and Infertility stands as a cornerstone in the provision of advanced reproductive healthcare. Our team is dedicated to offering a wide range of services tailored to address various reproductive health concerns, including hormonal disorders, infertility, and other aspects of reproductive and climacteric medicine. We provide a patient-centred approach at every vital stage of a woman’s life – from adolescence to reproductive age, and all the way to menopause. 
Our Team
Head of Division & Emeritus Consultant
Senior Consultant
Consultants
Associate Consultants
Clinical Associate
  • Dr Jennifer Felize Morato Sosa
Our Services

The Division offers a multidisciplinary approach to infertility management, considering both male and female factors that contribute to reproductive challenges. We offer a full range of fertility investigations and treatment options such as Intra-uterine Insemination (IUI), In-vitro Fertilisation (IVF), Intra-Cytoplasmic Sperm Injection (ICSI), Pre-implantation Genetic Testing (PGT) as well as embryo, oocyte, and sperm cryopreservation. 

Fertility problems in women, including:

  • Ovulation problems
  • Blocked fallopian tubes
  • Endometriosis
  • Polycystic ovary syndrome (PCOS)
  • Uterine adhesions
  • Parental genetic defects requiring pre-implantation genetic testing (PGT)
  • Fertility preservation in women with cancer
  • Other problems including ovarian cysts, fibroids, and a history of previous tubal sterilisation

Fertility problems in men, including:

  • Subfertility (e.g. low sperm count, motility or abnormal shape of sperm) 

Couples with:

Adolescent care:

  • Pubertal disorders (e.g. early puberty, delayed puberty, etc.)
  • Menstrual irregularities
  • Hirsutism
  • Congenital uterine anomalies
  • Teenage pregnancy

Menopause transition: 

  • Hormone replacement therapy
  • Premature ovarian insufficiency
  • Osteoporosis

Elective Egg Freezing:

From 1 July 2023, women aged 21 to less than 38 years will have the option to freeze their eggs for non-medical reasons. For more information, click here.

Pre-Implantation Genetic Testing

We offer three types of pre-implantation genetic testing (PGT). 

  • PGT for Monogenic Disorders (PGT-M)
  • PGT for Structural Rearrangements (PGT-SR)
  • PGT for Aneuploidies (PGT-A)

Couples will be referred to a genetics specialist prior to pre-implantation genetic testing for proper counselling.

PGT-M

PGT-M is done with either spouse has a known inheritable condition. It is performed on embryos collected after IVF to screen for specific genetic conditions.

PGT-SR

PGT-SR is done with either spouse has an abnormal chromosome number or structure that may increase the risk of a miscarriage or having a child with a chromosomal anomaly. It is performed by looking at the chromosome structure of the embryos collected after IVF. 

PGT-A

In Singapore, PGT-A can only be performed in public healthcare institutions when any of the following criteria are met:

  • The woman is at least 35 years old
  • Has had two or more previous miscarriages
  • Failed to get pregnant after two embryo transfers

PGT-A identifies embryos with abnormal chromosome numbers. This helps the doctor choose which embryo to transfer and results in higher implantation rates and lower miscarriage rates. 

Fertility Preservation

This reproductive technique allows women to preserve their ability to have biological children in cases where fertility may be compromised due to illness, cancer treatment, or surgery. It involves freezing sperm, eggs, embryos, or ovarian tissue. 

The patient must be referred by their primary cancer specialist to our fertility clinic. Upon review, a detailed assessment is done to begin fertility treatment soonest possible. 

What to Expect at Your First Appointment
On the first visit, couples will be seen at the Subfertility Clinic where a comprehensive review of their medical history and previous attempts at conception will be taken. A full physical examination will also be conducted. 

Initial fertility assessments may include female hormone blood tests, preconception blood tests, transvaginal ultrasound, test for tubal patency (hysterosalpingogram), and a semen analysis. The results will help the doctor decide on the appropriate fertility treatment for the couple. Fertility treatments will be carried out at the Clinic for Human Reproduction.
For More Information
For queries regarding pre-implantation genetic testing or fertility preservation, please contact us at [email protected].  
Find Us


Subfertility Clinic

Located within Women's Clinic Jade (Former Clinic G)

Opening Hours

Mon - Thu: 8:30am to 6:00pm
Fri: 8:30am to 5:30pm
Sat, Sun & PH: Closed

Location

NUH Kent Ridge Wing
Zone C
Level 3
C03-02

Contact: [email protected]


Clinic for Human Reproduction (CHR) 

The Clinic for Human Reproduction was established to address fertility issues in couples. Since its inception, we have made key discoveries that are vital to the advancement in the field of assisted reproduction. 

Opening Hours

Mon - Fri: 8:00am to 5:00pm
Sat: 8:30am to 12:30pm
Sun & PH: Closed

Location

NUH Kent Ridge Wing
Zone D
Level 4
D04-02

Contact: [email protected]


Women's Clinic - Emerald/Ruby

Opening Hours

Mon - Thu: 8.30am to 6.00pm
Fri: 8.30am to 5.30pm
Sat: 8.30am to 12.30pm 
Sun & PH: Closed

Location

NUH Kent Ridge Wing
Zone D
Level 3
D03-06

Contact: [email protected]

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