Paediatric Allergy and Immunology

Led by senior paediatricians, our team has trained both local and regional doctors and is involved in translational research.

• Dr Elizabeth Tham Huiwen

• Professor Hugo Van Bever
• Professor Lynette Shek
• Adj. Associate Professor Soh Jian Yi

• Dr Lydia Wong
• Dr Pauline Chan

• Dr Alison Lee
• Dr Zhong Youjia
• Dr Mohana Rajakulendran

• Senior Staff Nurse Ruth Chua
• Assistant Nurse Clinician Angela Kriselda Ramos Bueno

Our team serves children with a variety of conditions, including:

• Allergic Conjunctivitis
• Allergic Rhinitis and Aeroallergen Allergy
• Anaphylaxis
• Angioedema and Urticaria
• Asthma and other respiratory conditions

Our comprehensive paediatric asthma service provides management for both inpatient and outpatient care. Our holistic asthma programme encompasses detailed diagnosis, treatment, as well as extensive education and counselling.

Our facilities are equipped to conduct a range of lung function tests, including:

• Spirometry
• Exercise-stress tests 
• Exhaled nitric oxide evaluation
• Atopic Dermatitis or Eczema

We manage paediatric atopic dermatitis (commonly known as eczema) and conduct thorough evaluations to identify potential triggers, such as food allergies, offering patch testing where appropriate. Our holistic management approach includes education on trigger avoidance, skin care guidance, wet wrap therapy and child life therapy to assist patients in managing chronic eczema. For severe cases, we offer biologic therapy.

• Contact and Environmental Allergies
• Drug AllergiesEosinophilic Esophagitis and Gastroenteropathies
• Food Allergies
• Insect Sting Allergy
• Oral Allergy Syndrome
• Vaccine Adverse Events and related issues
• Immunodeficiency

We also provide comprehensive testing and services for children with allergies:

• Skin prick, intradermal and patch tests with commercial and customised allergy extracts
• Serum specific immunoglobulin E and component resolved diagnostics
• Oral food challenges
• Drug challenges and desensitisation procedures
• Skin care education and wet wrap therapy for eczema
• Biologic therapy for various allergic conditions
• Workup for Immune Related Disorders
• Immunotherapy
  • Sublingual immunotherapy for aeroallergens
  • Oral immunotherapy for food allergy
  • Subcutaneous immunotherapy for venom allergy

Immunodeficiency refers to conditions where an individual’s immune system, which is responsible for preventing and managing infections, functions sub-optimally. Consequently, these individuals may experience infections that are more frequent, severe or caused by unusual pathogens—distinct from the common viral infections and colds typically seen in children. Managing immunodeficiency often requires the collaboration of multiple medical specialties.

As a referral centre in Singapore, we provide a comprehensive range of diagnostic tests for immune deficiencies. These include the assessment of immunoglobulin levels, vaccine responses, lymphocyte subsets, lympho-proliferative tests, neutrophil function tests and cytokine measurements. 

We have a track record of successful transplants in children with complex primary immune deficiencies, such as Chronic Granulomatous Disease, Hyper-IgM syndrome and Leukocyte adhesion deficiency type 1.

How to send tests to Paediatric Allergy and Immunology Laboratory
Click here (PDF, 160 KB) for list of tests.

The I CAN! Programme is dedicated to the holistic care of children with asthma and/or allergies. The programme encompasses inpatient and outpatient care, acute care services, chronic outpatient management, as well as diagnostic and therapeutic facilities.

Please contact us at [email protected] to find out more about our programmes and upcoming events.

Learn how to use an EpiPen safely and correctly when your child experiences a severe allergic reaction in this video.

Learn how to use an inhaler directly and with a face mask and/or spacer in this video.